Panama gives you two coasts that behave nothing alike. The Pacific side has tides of 4 to 6 m, strong dry-season northerlies across the Bahía de Panamá from roughly December to April, and a chain of destinations: Taboga, Las Perlas (Contadora, Saboga, Pedro González, Isla del Rey), the Azuero coast, Coiba National Park and the Chiriquí islands. The Caribbean side has almost no tide, clear warm water, and San Blas, Portobelo and Linton, then Bocas del Toro to the west. There are no hurricanes on either coast, but the rainy season (roughly May to November) brings afternoon squalls and lightning, and the Caribbean gets a northerly swell from December to March that makes open anchorages uncomfortable.
The questions people ask: which coast suits my boat and my season, what permits and fees apply in San Blas and Coiba, and where can I actually get fuel, water and parts. San Blas is the Comarca Guna Yala, with its own community fees on top of national paperwork. Coiba is a MiAmbiente national park with entry fees and mooring rules. Fuel and chandlery are concentrated in Panama City, Colón, Bocas and a few fishing ports.
This collection will cover cruising the Pacific coast from Panama City to Chiriquí, cruising the Caribbean coast from Colón to Bocas, San Blas by boat with Guna permits and etiquette, Las Perlas anchorages, Pacific tides and currents, Panama's boating seasons, and fuel, water, parts and provisioning for cruisers. Panama City pages on Las Perlas, Taboga and the Bahía de Panamá are live now, as are the marina pages for Linton Bay, Panamarina, Bocas and Boca Chica.
Coming from the US, the nearest Florida page is the Florida to Bahamas boat trip guide; the planning habits translate, the tides and reef permits do not.